Potential Role for the Metnase Transposase Fusion Gene in Colon Cancer through the Regulation of Key Genes

The Metnase fusion gene consists of a SET histone methyltransferase domain and a transposase domain from Mariner transposase. This transposable element is involved in chromosome decatenation, enhances DNA repair, promotes foreign DNA integration, and assists topoisomerase II function. This study inv...

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Bibliografiske detaljer
Main Authors: Apostolou, Panagiotis, Toloudi, Maria, Kourtidou, Eleni, Mimikakou, Georgia, Vlachou, Ioanna, Chatziioannou, Marina, Kipourou, Vasiliki, Papasotiriou, Ioannis
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198141/
https://ncbi.nlm.nih.gov/pubmed/25333365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109741
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