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Bicaudal-D1 regulates the intracellular sorting and signalling of neurotrophin receptors

We have identified a new function for the dynein adaptor Bicaudal D homolog 1 (BICD1) by screening a siRNA library for genes affecting the dynamics of neurotrophin receptor-containing endosomes in motor neurons (MNs). Depleting BICD1 increased the intracellular accumulation of brain-derived neurotro...

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Detalhes bibliográficos
Main Authors: Terenzio, Marco, Golding, Matthew, Russell, Matthew R G, Wicher, Krzysztof B, Rosewell, Ian, Spencer-Dene, Bradley, Ish-Horowicz, David, Schiavo, Giampietro
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198053/
https://ncbi.nlm.nih.gov/pubmed/24920579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201387579
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