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Molecular basis of crosstalk between oncogenic Ras and the master regulator of hematopoiesis GATA-2
Disease mutations provide unique opportunities to decipher protein and cell function. Mutations in the master regulator of hematopoiesis GATA-2 underlie an immunodeficiency associated with myelodysplastic syndrome and leukemia. We discovered that a GATA-2 disease mutant (T354M) defective in chromati...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BlackWell Publishing Ltd
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4198037/ https://ncbi.nlm.nih.gov/pubmed/25056917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201438808 |
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