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Early Intervention with an Estrogen Receptor β-Selective Phytoestrogenic Formulation Prolongs Survival, Improves Spatial Recognition Memory, and Slows Progression of Amyloid Pathology in a Female Mouse Model of Alzheimer’s Disease

Our recent developments have yielded a novel phytoestrogenic formulation, referred to as the phyto-β-SERM formulation, which exhibits an 83-fold binding selectivity for the estrogen receptor subtype β (ERβ) over ERα. Earlier studies indicate that the phyto-β-SERM formulation is neuroprotective and p...

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Detalhes bibliográficos
Main Authors: Zhao, Liqin, Mao, Zisu, Chen, Shuhua, Schneider, Lon S., Brinton, Roberta D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197935/
https://ncbi.nlm.nih.gov/pubmed/23948892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-122341
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