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Murine Langerin(+) dermal dendritic cells prime CD8(+) T cells while Langerhans cells induce cross-tolerance

Skin dendritic cells (DCs) control the immunogenicity of cutaneously administered vaccines. Antigens targeted to DCs via the C-type lectin Langerin/CD207 are cross-presented to CD8(+) T cells in vivo. We investigated the relative roles of Langerhans cells (LCs) and Langerin(+) dermal DCs (dDCs) in d...

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書誌詳細
主要な著者: Flacher, Vincent, Tripp, Christoph H, Mairhofer, David G, Steinman, Ralph M, Stoitzner, Patrizia, Idoyaga, Juliana, Romani, Nikolaus
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Ltd 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197865/
https://ncbi.nlm.nih.gov/pubmed/25085878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201303283
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