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Pin1-dependent signalling negatively affects GABAergic transmission by modulating neuroligin2/gephyrin interaction

The cell adhesion molecule Neuroligin2 (NL2) is localized selectively at GABAergic synapses, where it interacts with the scaffolding protein gephyrin in the post-synaptic density. However, the role of this interaction for formation and plasticity of GABAergic synapses is unclear. Here, we demonstrat...

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Detalhes bibliográficos
Main Authors: Antonelli, Roberta, Pizzarelli, Rocco, Pedroni, Andrea, Fritschy, Jean-Marc, Del Sal, Giannino, Cherubini, Enrico, Zacchi, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197815/
https://ncbi.nlm.nih.gov/pubmed/25297980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6066
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