FtsH is required for proteolytic elimination of uncomplexed forms of SecY, an essential protein translocase subunit.
When secY is overexpressed over secE or secE is underexpressed, a fraction of SecY protein is rapidly degraded in vivo. This proteolysis was unaffected in previously described protease-defective mutants examined. We found, however, that some mutations in ftsH, encoding a membrane protein that belong...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1995
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41978/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7753838/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.10.4532 |
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