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Lymphotropic HCV strain can infect human primary naïve CD4(+) cells and affect their proliferation and IFN-γ secretion activity

BACKGROUND: Lymphotropic hepatitis C virus (HCV) infection of B and T cells might play an important role in the pathogenesis of hepatitis C. Recently, we showed that a lymphotropic HCV (SB strain) could infect established T-cell lines and B-cell lines. However, whether HCV replication interferes wit...

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Autores principales: Kondo, Yasuteru, Ueno, Yoshiyuki, Kakazu, Eiji, Kobayashi, Koju, Shiina, Masaaki, Tamai, Keiichi, Machida, Keigo, Inoue, Jun, Wakui, Yuta, Fukushima, Koji, Obara, Noriyuki, Kimura, Osamu, Shimosegawa, Tooru
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197795/
https://ncbi.nlm.nih.gov/pubmed/20714907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00535-010-0297-2
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