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The conserved LIM domain-containing focal adhesion protein ZYX-1 regulates synapse maintenance in Caenorhabditis elegans

We describe the identification of zyxin as a regulator of synapse maintenance in mechanosensory neurons in C. elegans. zyx-1 mutants lacked PLM mechanosensory synapses as adult animals. However, most PLM synapses initially formed during development but were subsequently lost as the animals developed...

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Detalhes bibliográficos
Main Authors: Luo, Shuo, Schaefer, Anneliese M., Dour, Scott, Nonet, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197707/
https://ncbi.nlm.nih.gov/pubmed/25252943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.108217
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