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Multiple roles for HOXA3 in regulating thymus and parathyroid differentiation and morphogenesis in mouse

Hoxa3 was the first Hox gene to be mutated by gene targeting in mice and is required for the development of multiple endoderm and neural crest cell (NCC)-derived structures in the pharyngeal region. Previous studies have shown that the Hoxa3 null mutant lacks third pharyngeal pouch derivatives, the...

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Détails bibliographiques
Auteurs principaux: Chojnowski, Jena L., Masuda, Kyoko, Trau, Heidi A., Thomas, Kirk, Capecchi, Mario, Manley, Nancy R.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197593/
https://ncbi.nlm.nih.gov/pubmed/25249461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.110833
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