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Multiple roles for HOXA3 in regulating thymus and parathyroid differentiation and morphogenesis in mouse

Hoxa3 was the first Hox gene to be mutated by gene targeting in mice and is required for the development of multiple endoderm and neural crest cell (NCC)-derived structures in the pharyngeal region. Previous studies have shown that the Hoxa3 null mutant lacks third pharyngeal pouch derivatives, the...

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Detalhes bibliográficos
Main Authors: Chojnowski, Jena L., Masuda, Kyoko, Trau, Heidi A., Thomas, Kirk, Capecchi, Mario, Manley, Nancy R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197593/
https://ncbi.nlm.nih.gov/pubmed/25249461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.110833
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