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Multiple roles for HOXA3 in regulating thymus and parathyroid differentiation and morphogenesis in mouse

Hoxa3 was the first Hox gene to be mutated by gene targeting in mice and is required for the development of multiple endoderm and neural crest cell (NCC)-derived structures in the pharyngeal region. Previous studies have shown that the Hoxa3 null mutant lacks third pharyngeal pouch derivatives, the...

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Autores principales: Chojnowski, Jena L., Masuda, Kyoko, Trau, Heidi A., Thomas, Kirk, Capecchi, Mario, Manley, Nancy R.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197593/
https://ncbi.nlm.nih.gov/pubmed/25249461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.110833
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