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Lipid rafts couple class A scavenger receptors to phospholipase A(2) activation during macrophage adhesion

SR-A mediated macrophage adhesion to modified ECM proteins in a process that involves physical attachment of SR-A to modified ECM and activation of Lyn-PI3K and PLA(2)-12/15-lipoxygenase signaling pathways. Structurally, SR-A-mediated cell adhesion requires a 6-aa membrane-proximal cytoplasmic motif...

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Détails bibliographiques
Auteurs principaux: Vadali, Shanthi, Post, Steven R.
Format: Artigo
Langue:Inglês
Publié: Society for Leukocyte Biology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197562/
https://ncbi.nlm.nih.gov/pubmed/25070949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.2A0414-214R
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