G1 phase arrest induced by Wilms tumor protein WT1 is abrogated by cyclin/CDK complexes.
WT1, the Wilms tumor-suppressor gene, maps to the human chromosomal region 11p13 and encodes a transcriptional repressor, WT1, implicated in controlling normal urogenital development. Microinjection of the WT1 cDNA into quiescent cells or cells in early to mid G1 phase blocked serum-induced cell cyc...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41975/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7753836/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.10.4517 |
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