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siRNA-Mediated Suppression of Synuclein γ Inhibits MDA-MB-231 Cell Migration and Proliferation by Downregulating the Phosphorylation of AKT and ERK

PURPOSE: Synuclein-γ (SNCG), which was initially identified as breast cancer specific gene 1, is highly expressed in advanced breast cancers, but not in normal or benign breast tissue. This study aimed to evaluate the effects of SNCG siRNA-treatment on breast cancer cells and elucidate the associate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: He, Jingsong, Xie, Ni, Yang, Jianbo, Guan, Hong, Chen, Weicai, Wu, Huisheng, Yuan, Zishan, Wang, Kun, Li, Guojin, Sun, Jie, Yu, Limin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Breast Cancer Society 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197349/
https://ncbi.nlm.nih.gov/pubmed/25320617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4048/jbc.2014.17.3.200
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