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Learning and Memory Deficits Upon TAU Accumulation in Drosophila Mushroom Body Neurons

Mutations in the neuronal-specific microtubule-binding protein TAU are associated with several dementias and neurodegenerative diseases. However, the effects of elevated TAU accumulation on behavioral plasticity are unknown. We report that directed expression of wild-type vertebrate and Drosophila T...

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Autors principals: Mershin, Andreas, Pavlopoulos, Elias, Fitch, Olivia, Braden, Brittany C., Nanopoulos, Dimitri V., Skoulakis, Efthimios M.C.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC419730/
https://ncbi.nlm.nih.gov/pubmed/15169857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.70804
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