Failure of combined antiretroviral therapy intensification with maraviroc and raltegravir in chronically HIV-1 infected patients to reduce the viral reservoir: the IntensHIV randomized trial

BACKGROUND: Ongoing HIV-1 replication in lymphoid cells is one explanation of the persistence of HIV-1 reservoirs despite highly active antiretroviral therapy (cART). We tested the potential of cART intensification by Maraviroc plus Raltegravir to decrease proviral HIV-1 DNA levels in lymphoid cells...

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Detalhes bibliográficos
Main Authors: Lafeuillade, Alain, Assi, Assi, Poggi, Cécile, Bresson-Cuquemelle, Caroline, Jullian, Eric, Tamalet, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197239/
https://ncbi.nlm.nih.gov/pubmed/25320633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-11-33
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