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A dynamic set point for thermal adaptation requires phospholipase C-mediated regulation of TRPM8 in vivo

The ability to sense and respond to thermal stimuli at varied environmental temperatures is essential for survival in seasonal areas. In this study, we show that mice respond similarly to ramping changes in temperature from a wide range of baseline temperatures. Further investigation suggests that t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Brenner, Daniel S., Golden, Judith P., Vogt, Sherri K., Dhaka, Ajay, Story, Gina M., Gereau, Robert W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197096/
https://ncbi.nlm.nih.gov/pubmed/25109670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2014.08.001
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