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Hypoxic conditions differentially regulate TAZ and YAP in cancer cells
The Hippo-YAP pathway is altered and implicated as an oncogenic signaling pathway in many human cancers. Hypoxia is an important microenvironmental factor that promotes tumorigenesis. However, the effects of hypoxia on the two most important Hippo-YAP effectors, YAP (Yes-associated protein) and TAZ...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197065/ https://ncbi.nlm.nih.gov/pubmed/25078107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2014.07.024 |
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