A Novel Model of Chronic Wounds: Importance of Redox Imbalance and Biofilm-Forming Bacteria for Establishment of Chronicity

Chronic wounds have a large impact on health, affecting ∼6.5 M people and costing ∼$25B/year in the US alone [1]. We previously discovered that a genetically modified mouse model displays impaired healing similar to problematic wounds in humans and that sometimes the wounds become chronic. Here we s...

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Main Authors: Dhall, Sandeep, Do, Danh, Garcia, Monika, Wijesinghe, Dayanjan Shanaka, Brandon, Angela, Kim, Jane, Sanchez, Antonio, Lyubovitsky, Julia, Gallagher, Sean, Nothnagel, Eugene A., Chalfant, Charles E., Patel, Rakesh P., Schiller, Neal, Martins-Green, Manuela
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196950/
https://ncbi.nlm.nih.gov/pubmed/25313558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109848
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