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Pyrroloquinoline Quinone (PQQ) Inhibits Lipopolysaccharide Induced Inflammation in Part via Downregulated NF-κB and p38/JNK Activation in Microglial and Attenuates Microglia Activation in Lipopolysaccharide Treatment Mice

Therapeutic strategies designed to inhibit the activation of microglia may lead to significant advancement in the treatment of most neurodegenerative diseases. Pyrroloquinoline quinone (PQQ) is a naturally occurring redox cofactor that acts as an essential nutrient, antioxidant, and has been reporte...

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Bibliografiske detaljer
Main Authors: Yang, Chongfei, Yu, Lifeng, Kong, Lingbo, Ma, Rui, Zhang, Juliang, Zhu, Qingsheng, Zhu, Jinyu, Hao, Dingjun
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196908/
https://ncbi.nlm.nih.gov/pubmed/25314304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109502
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