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Brain renin-angiotensin system blockade by systemically active aminopeptidase A inhibitors: A potential treatment of salt-dependent hypertension

The hyperactivity of the brain renin-angiotensin system (RAS) has been implicated in the development and maintenance of hypertension in several types of experimental and genetic hypertension animal models. We previously reported that in the murine brain, aminopeptidase A (APA) is involved in the con...

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Detalhes bibliográficos
Main Authors: Fournie-Zaluski, Marie-Claude, Fassot, Celine, Valentin, Bruno, Djordjijevic, Dragan, Reaux-Le Goazigo, Annabelle, Corvol, Pierre, Roques, Bernard P., Llorens-Cortes, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419682/
https://ncbi.nlm.nih.gov/pubmed/15136730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402312101
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