A Conserved Endoplasmic Reticulum Membrane Protein Complex (EMC) Facilitates Phospholipid Transfer from the ER to Mitochondria

Mitochondrial membrane biogenesis and lipid metabolism require phospholipid transfer from the endoplasmic reticulum (ER) to mitochondria. Transfer is thought to occur at regions of close contact of these organelles and to be nonvesicular, but the mechanism is not known. Here we used a novel genetic...

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Autors principals: Lahiri, Sujoy, Chao, Jesse T., Tavassoli, Shabnam, Wong, Andrew K. O., Choudhary, Vineet, Young, Barry P., Loewen, Christopher J. R., Prinz, William A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196738/
https://ncbi.nlm.nih.gov/pubmed/25313861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001969
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