A Conserved Endoplasmic Reticulum Membrane Protein Complex (EMC) Facilitates Phospholipid Transfer from the ER to Mitochondria

Mitochondrial membrane biogenesis and lipid metabolism require phospholipid transfer from the endoplasmic reticulum (ER) to mitochondria. Transfer is thought to occur at regions of close contact of these organelles and to be nonvesicular, but the mechanism is not known. Here we used a novel genetic...

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Bibliographic Details
Main Authors: Lahiri, Sujoy, Chao, Jesse T., Tavassoli, Shabnam, Wong, Andrew K. O., Choudhary, Vineet, Young, Barry P., Loewen, Christopher J. R., Prinz, William A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196738/
https://ncbi.nlm.nih.gov/pubmed/25313861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001969
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