Effect of Extended Release Niacin on Serum Lipids and on Endothelial Function in Adults with Sickle Cell Anemia and Low High-Density Lipoprotein Cholesterol Levels

Through bound apolipoprotein A-I (apoA-I), high density lipoprotein cholesterol (HDL-C) activates endothelial nitric oxide synthase, inducing vasodilation. Because patients with sickle cell disease (SCD)have low apoA-I andendothelial dysfunction,we conducted a randomized, double-blinded, placebo-con...

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Autors principals: Scoffone, Heather M., Krajewski, Megan, Zorca, Suzana, Bereal-Williams, Candice, Littel, Patricia, Seamon, Catherine, Mendelsohn, Laurel, Footman, Eleni, Jaoudeh, Nadine Abi, Sachdev, Vandana, Machado, Roberto F., Cuttica, Michael, Shamburek, Robert, Cannon, Richard O., Remaley, Alan, Minniti, Caterina P., Kato, Gregory J.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196719/
https://ncbi.nlm.nih.gov/pubmed/24035168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjcard.2013.06.035
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