Characterization of the effect of LPS on dendritic cell subset discrimination in spleen

The Gram-negative bacterial endotoxin lipopolysaccharide (LPS) is a potent inflammatory mediator and a leading cause of bacterial sepsis. While LPS is known to activate antigen-presenting cells, here we find that LPS down-regulates expression of CD11c and CD11b on splenic dendritic cell subsets, thu...

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Bibliographic Details
Main Authors: Griffiths, Kristin L, Tan, Jonathan KH, O'Neill, Helen C
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2014
Subjects:
Short Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196665/
https://ncbi.nlm.nih.gov/pubmed/24913604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12332
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