Up-regulated HMGB1 in EAM directly led to collagen deposition by a PKCβ/Erk1/2-dependent pathway: cardiac fibroblast/myofibroblast might be another source of HMGB1

High mobility group box 1 (HMGB1), an important inflammatory mediator, is actively secreted by immune cells and some non-immune cells or passively released by necrotic cells. HMGB1 has been implicated in many inflammatory diseases. Our previous published data demonstrated that HMGB1 was up-regulated...

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Hlavní autoři: Su, Zhaoliang, Yin, Jingping, Wang, Ting, Sun, Yingkun, Ni, Ping, Ma, Rui, Zhu, Haitao, Zheng, Dong, Shen, Huiling, Xu, Wenlin, Xu, Huaxi
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2014
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196650/
https://ncbi.nlm.nih.gov/pubmed/24912759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12324
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