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State Transitions in the TORC1 Signaling Pathway and Information Processing in Saccharomyces cerevisiae

TOR kinase complex I (TORC1) is a key regulator of cell growth and metabolism in all eukaryotes. Previous studies in yeast have shown that three GTPases—Gtr1, Gtr2, and Rho1—bind to TORC1 in nitrogen and amino acid starvation conditions to block phosphorylation of the S6 kinase Sch9 and activate pro...

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Detalhes bibliográficos
Main Authors: Hughes Hallett, James E., Luo, Xiangxia, Capaldi, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196627/
https://ncbi.nlm.nih.gov/pubmed/25085507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.168369
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