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Ellis Englesberg and the Discovery of Positive Control in Gene Regulation
Based on his work with the Escherichia coli l-arabinose operon, Ellis Englesberg proposed in 1965 that the regulatory gene araC was an “activator gene” required for positive control of the ara operon. This challenged the widely held belief in a universal mechanism of negative regulation proposed ear...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Genetics Society of America
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4196604/ https://ncbi.nlm.nih.gov/pubmed/25316786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.167361 |
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