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The effect of interspecific oocytes on demethylation of sperm DNA

In contrast to mice, in sheep no genome-wide demethylation of the paternal genome occurs within the first postfertilization cell cycle. This difference could be due either to an absence of a sheep demethylase activity that is present in mouse ooplasm or to an increased protection of methylated cytos...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Beaujean, Nathalie, Taylor, Jane E., McGarry, Michelle, Gardner, John O., Wilmut, Ian, Loi, Pasqualino, Ptak, Grazyna, Galli, Cesare, Lazzari, Giovanna, Bird, Adrian, Young, Lorraine E., Meehan, Richard R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419658/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15136736/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0400730101
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