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Endogenous NO regulates superoxide production at low oxygen concentrations by modifying the redox state of cytochrome c oxidase

We have investigated in whole cells whether, at low oxygen concentrations ([O(2)]), endogenous nitric oxide (NO) modulates the redox state of the mitochondrial electron transport chain (ETC), and whether such an action has any signaling consequences. Using a polarographic-and-spectroscopic-coupled s...

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Detalhes bibliográficos
Main Authors: Palacios-Callender, Miriam, Quintero, Marisol, Hollis, Veronica S., Springett, Roger J., Moncada, Salvador
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419657/
https://ncbi.nlm.nih.gov/pubmed/15136725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401723101
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