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Use of induced pluripotent stem cell derived neurons engineered to express BDNF for modulation of stressor related pathology

Combined cell and gene-based therapeutic strategies offer potential in the treatment of neurodegenerative and psychiatric conditions that have been associated with structural brain disturbances. In the present investigation, we used a novel virus-free re-programming method to generate induced plurip...

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Hlavní autoři: Liu, Gele, Rustom, Nazneen, Litteljohn, Darcy, Bobyn, Jessica, Rudyk, Chris, Anisman, Hymie, Hayley, Shawn
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196567/
https://ncbi.nlm.nih.gov/pubmed/25352778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00316
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