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Angiogenin stimulates ribosomal RNA transcription by epigenetic activation of the ribosomal DNA promoter
Angiogenin (ANG) undergoes nuclear translocation and promotes ribosomal RNA (rRNA) transcription thereby enhancing cell growth and proliferation. However, the mode of action of ANG in stimulating rRNA transcription is unclear. Here, we show that ANG enhances the formation of RNA polymerase I (Pol I)...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4196338/ https://ncbi.nlm.nih.gov/pubmed/24122807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24477 |
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