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Angiogenin stimulates ribosomal RNA transcription by epigenetic activation of the ribosomal DNA promoter

Angiogenin (ANG) undergoes nuclear translocation and promotes ribosomal RNA (rRNA) transcription thereby enhancing cell growth and proliferation. However, the mode of action of ANG in stimulating rRNA transcription is unclear. Here, we show that ANG enhances the formation of RNA polymerase I (Pol I)...

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Bibliografische gegevens
Hoofdauteurs: SHENG, JINGHAO, YU, WENHAO, GAO, XIANGWEI, XU, ZHENGPING, HU, GUO-FU
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196338/
https://ncbi.nlm.nih.gov/pubmed/24122807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24477
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