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Angiogenin stimulates ribosomal RNA transcription by epigenetic activation of the ribosomal DNA promoter

Angiogenin (ANG) undergoes nuclear translocation and promotes ribosomal RNA (rRNA) transcription thereby enhancing cell growth and proliferation. However, the mode of action of ANG in stimulating rRNA transcription is unclear. Here, we show that ANG enhances the formation of RNA polymerase I (Pol I)...

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Autors principals: SHENG, JINGHAO, YU, WENHAO, GAO, XIANGWEI, XU, ZHENGPING, HU, GUO-FU
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196338/
https://ncbi.nlm.nih.gov/pubmed/24122807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24477
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