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Ethanol Administration Produces Divergent Changes in GABAergic Neuroactive Steroid Immunohistochemistry in the Rat Brain

BACKGROUND: The 5α-reduced pregnane neuroactive steroid (3α,5α)-3-hydroxypregnan-20-one (3α,5α-THP or allopregnanolone) is a potent positive modulator of GABA(A) receptors capable of modulating neuronal activity. In rats, systemic ethanol administration increases cerebral cortical and hippocampal le...

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Detalhes bibliográficos
Main Authors: Cook, Jason B., Dumitru, Ana Maria G., O’Buckley, Todd K., Morrow, A. Leslie
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196317/
https://ncbi.nlm.nih.gov/pubmed/23906006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12223
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