HDAC inhibitors and immunotherapy; a double edged sword?

Epigenetic modifications, like histone acetylation, are essential for regulating gene expression within cells. Cancer cells acquire pathological epigenetic modifications resulting in gene expression patterns that facilitate and sustain tumorigenesis. Epigenetic manipulation therefore is emerging as...

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Detalles Bibliográficos
Main Authors: Kroesen, Michiel, Gielen, Paul, Brok, Ingrid C., Armandari, Inna, Hoogerbrugge, Peter M., Adema, Gosse J.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2014
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196144/
https://ncbi.nlm.nih.gov/pubmed/25115382
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