HDAC inhibitors and immunotherapy; a double edged sword?

Epigenetic modifications, like histone acetylation, are essential for regulating gene expression within cells. Cancer cells acquire pathological epigenetic modifications resulting in gene expression patterns that facilitate and sustain tumorigenesis. Epigenetic manipulation therefore is emerging as...

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Bibliographische Detailangaben
Hauptverfasser: Kroesen, Michiel, Gielen, Paul, Brok, Ingrid C., Armandari, Inna, Hoogerbrugge, Peter M., Adema, Gosse J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196144/
https://ncbi.nlm.nih.gov/pubmed/25115382
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