Intestinal and Hepatic Expression of Cytochrome P450s and mdr1a in Rats with Indomethacin-Induced Small Intestinal Ulcers

Background: Non-steroidal anti-inflammatory drugs induce the serious side effect of small intestinal ulcerations (SIUs), but little information is available regarding the consequences to drug metabolism and absorption. Aim: We examined the existence of secondary hepatic inflammation in rats with ind...

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Autors principals: Kawauchi, Shoji, Nakamura, Tsutomu, Yasui, Hiroyuki, Nishikawa, Chikako, Miki, Ikuya, Inoue, Jun, Horibe, Sayo, Hamaguchi, Tsuneo, Tanahashi, Toshihito, Mizuno, Shigeto
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196121/
https://ncbi.nlm.nih.gov/pubmed/25317066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.9866
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