The adult heart responds to increased workload with physiologic hypertrophy, cardiac stem cell activation, and new myocyte formation

AIMS: It is a dogma of cardiovascular pathophysiology that the increased cardiac mass in response to increased workload is produced by the hypertrophy of the pre-existing myocytes. The role, if any, of adult-resident endogenous cardiac stem/progenitor cells (eCSCs) and new cardiomyocyte formation in...

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Main Authors: Waring, Cheryl D., Vicinanza, Carla, Papalamprou, Angela, Smith, Andrew J., Purushothaman, Saranya, Goldspink, David F., Nadal-Ginard, Bernardo, Torella, Daniele, Ellison, Georgina M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Basic Science
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196078/
https://ncbi.nlm.nih.gov/pubmed/23100284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehs338
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