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Allosteric regulation of rhomboid intramembrane proteolysis

Proteolysis within the lipid bilayer is poorly understood, in particular the regulation of substrate cleavage. Rhomboids are a family of ubiquitous intramembrane serine proteases that harbour a buried active site and are known to cleave transmembrane substrates with broad specificity. In vitro gel a...

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Autores principales: Arutyunova, Elena, Panwar, Pankaj, Skiba, Pauline M, Gale, Nicola, Mak, Michelle W, Lemieux, M Joanne
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195783/
https://ncbi.nlm.nih.gov/pubmed/25009246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488149
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