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Reduced pachytene piRNAs and translation underlie spermiogenic arrest in Maelstrom mutant mice

Pachytene piRNAs are a class of Piwi-interacting small RNAs abundant in spermatids of the adult mouse testis. They are processed from piRNA primary transcripts by a poorly understood mechanism and, unlike fetal transposon-derived piRNAs, lack complementary targets in the spermatid transcriptome. We...

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Autores principales: Castañeda, Julio, Genzor, Pavol, van der Heijden, Godfried W, Sarkeshik, Ali, Yates, John R, Ingolia, Nicholas T, Bortvin, Alex
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195769/
https://ncbi.nlm.nih.gov/pubmed/25063675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201386855
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