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The minimal promoter plays a major role in silencing of the galago γ-globin gene in adult erythropoiesis

The human γ-globin gene and its orthologous galago γ-globin gene evolved from an ancestral ε-globin gene. In galago, expression of the γ-gene remained restricted to the embryonic stage of development, whereas in humans, expression of the γ-gene was recruited to the fetal stage. To localize the cis-e...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Li, Qiliang, Fang, Xiangdong, Han, Hemei, Stamatoyannopoulos, George
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419563/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15148375/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0402594101
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