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Bio-Inspired Synthetic Nanovesicles for Glucose-Responsive Release of Insulin

[Image: see text] A new glucose-responsive formulation for self-regulated insulin delivery was constructed by packing insulin, glucose-specific enzymes into pH-sensitive polymersome-based nanovesicles assembled by a diblock copolymer. Glucose can passively transport across the bilayer membrane of th...

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Bibliografiske detaljer
Main Authors: Tai, Wanyi, Mo, Ran, Di, Jin, Subramanian, Vinayak, Gu, Xiao, Buse, John B., Gu, Zhen
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195518/
https://ncbi.nlm.nih.gov/pubmed/25268758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm500364a
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