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Regional Heritability Mapping to identify loci underlying genetic variation of complex traits

BACKGROUND: Genome-wide association studies can have limited power to identify QTL, partly due to the stringent correction for multiple testing and low linkage-disequilibrium between SNPs and QTL. Regional Heritability Mapping (RHM) has been advanced as an alternative approach to capture underlying...

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Detalhes bibliográficos
Main Authors: Riggio, Valentina, Pong-Wong, Ricardo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195407/
https://ncbi.nlm.nih.gov/pubmed/25519517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S5-S3
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