The effect of selective phosphodiesterase inhibitors, alone and in combination, on a murine model of allergic asthma

BACKGROUND: The anti-inflammatory effects of the selective phosphodiesterase (PDE) inhibitors cilostazol (PDE 3), RO 20-1724 (PDE 4) and sildenafil (PDE 5) were examined in a murine model of allergic asthma. These compounds were used alone and in combination to determine any potential synergism, wit...

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Detalhes bibliográficos
Main Authors: Clayton, Robert A, Dick, Colin AJ, Mackenzie, Alison, Nagasawa, Michiaki, Galbraith, Deirdre, Hastings, Stuart F, MacKenzie, Simon J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419478/
https://ncbi.nlm.nih.gov/pubmed/15169552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-5-4
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