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Preferential binding to branched DNA strands and strand-annealing activity of the human Rad51B, Rad51C, Rad51D and Xrcc2 protein complex

The Rad51B, Rad51C, Rad51D and Xrcc2 proteins are Rad51 paralogs, and form a complex (BCDX2 complex) in mammalian cells. Mutant cells defective in any one of the Rad51-paralog genes exhibit spontaneous genomic instability and extreme sensitivity to DNA-damaging agents, due to inefficient recombinati...

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Detalhes bibliográficos
Main Authors: Yokoyama, Hiroshi, Sarai, Naoyuki, Kagawa, Wataru, Enomoto, Rima, Shibata, Takehiko, Kurumizaka, Hitoshi, Yokoyama, Shigeyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419466/
https://ncbi.nlm.nih.gov/pubmed/15141025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh578
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