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Sequence–structure–function studies of tRNA:m(5)C methyltransferase Trm4p and its relationship to DNA:m(5)C and RNA:m(5)U methyltransferases
Three types of methyltransferases (MTases) generate 5-methylpyrimidine in nucleic acids, forming m(5)U in RNA, m(5)C in RNA and m(5)C in DNA. The DNA:m(5)C MTases have been extensively studied by crystallographic, biophysical, biochemical and computational methods. On the other hand, the sequence–st...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2004
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419452/ https://ncbi.nlm.nih.gov/pubmed/15121902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh564 |
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