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Synapsis and DNA cleavage in φC31 integrase-mediated site-specific recombination

The Streptomyces phage φC31 encodes an integrase belonging to the serine recombinase family of site-specific recombinases. The well studied serine recombinases, the resolvase/invertases, bring two recombination sites together in a synapse, and then catalyse a concerted four-strand staggered break in...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Smith, Matthew C. A., Till, Rob, Brady, Kevin, Soultanas, Panos, Thorpe, Helena, Smith, Margaret C. M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2004
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419440/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15141031/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh538
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