Enhanced Venous Thrombus Resolution in Plasminogen Activator Inhibitor Type-2 Deficient Mice

BACKGROUND: The resolution of deep vein thrombosis (DVT) requires an inflammatory response and mobilization of proteases, such as urokinase-type plasminogen activator (uPA) and matrix metalloproteinases (MMPs), to degrade the thrombus and remodel the injured vein wall. PAI-2 is a serine protease inh...

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Detalhes bibliográficos
Main Authors: Siefert, Suzanne A, Chabasse, Christine, Mukhopadhyay, Subhradip, Hoofnagle, Mark H, Strickland, Dudley K, Sarkar, Rajabrata, Antalis, Toni M
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194171/
https://ncbi.nlm.nih.gov/pubmed/25041188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12657
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