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Chronic Central Nervous System Expression of HIV-1 Tat Leads to Accelerated Rarefaction of Neocortical Capillaries and Loss of Red Blood Cell Velocity Heterogeneity

OBJECTIVES: HIV-1 infection of the central nervous system is associated with impairment of cerebral blood flow and neurocognitive function, and accelerated signs of aging. Since normal aging is associated with rarefaction of the cerebral vasculature, we set out to examine chronic viral effects on th...

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Detalhes bibliográficos
Main Authors: Silva, Jharon N., Polesskaya, Oksana, Wei, Helen S., Rasheed, Izad-Yar D., Chamberlain, Jeffrey M., Nishimura, Christopher, Feng, Changyong, Dewhurst, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194156/
https://ncbi.nlm.nih.gov/pubmed/24813724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12145
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