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Role of Phospholipase D in G-Protein Coupled Receptor Function

Prolonged agonist exposure of many G-protein coupled receptors induces a rapid receptor phosphorylation and uncoupling from G-proteins. Resensitization of these desensitized receptors requires endocytosis and subsequent dephosphorylation. Numerous studies show the involvement of phospholipid-specifi...

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Detalhes bibliográficos
Main Authors: Brandenburg, Lars-Ove, Pufe, Thomas, Koch, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194036/
https://ncbi.nlm.nih.gov/pubmed/24995811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/membranes4030302
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