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Surveillance of nuclear pore complex assembly by ESCRT-III/Vps4

The maintenance of nuclear compartmentalization by the nuclear envelope and nuclear pore complexes (NPCs) is essential for cell function; loss of compartmentalization is associated with cancers, laminopathies and aging. We uncovered a pathway that surveils NPC assembly intermediates to promote the f...

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Détails bibliographiques
Auteurs principaux: Webster, Brant M., Colombi, Paolo, Jäger, Jens, Lusk, C. Patrick
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194032/
https://ncbi.nlm.nih.gov/pubmed/25303532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.09.012
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