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The Trypanosoma cruzi flagellum is discarded via asymmetric cell division following invasion and provides early targets for protective CD8(+) T cells

During invasion of host cells by Trypanosoma cruzi, the parasite that causes Chagas disease, the elongated, flagellated trypomastigotes remodel into oval amastigotes with no external flagellum. The underlying mechanism of this remodeling and the fate of the flagellum are obscure. We discovered that...

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Detalhes bibliográficos
Main Authors: Kurup, Samarchith P., Tarleton, Rick L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194031/
https://ncbi.nlm.nih.gov/pubmed/25299330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.09.003
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