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Transcription and processing: multilayer controls of RNA biogenesis by the Hippo pathway
The Hippo pathway plays a critical role in organ size control and tumorigenesis. YAP (and also its homologue TAZ) is a transcription co-activator that mediates the biological functions of the Hippo pathway. YAP activity is inhibited upon phosphorylation by the Lats kinases (reviewed in Yu & Guan...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BlackWell Publishing Ltd
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4193929/ https://ncbi.nlm.nih.gov/pubmed/24639555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201488329 |
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