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Dendritic cell maturation: functional specialization through signaling specificity and transcriptional programming
Dendritic cells (DC) are key regulators of both protective immune responses and tolerance to self-antigens. Soon after their discovery in lymphoid tissues by Steinman and Cohn, as cells with the unique ability to prime naïve antigen-specific T cells, it was realized that DC can exist in at least two...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BlackWell Publishing Ltd
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4193918/ https://ncbi.nlm.nih.gov/pubmed/24737868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201488027 |
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