Dendritic cell maturation: functional specialization through signaling specificity and transcriptional programming

Dendritic cells (DC) are key regulators of both protective immune responses and tolerance to self-antigens. Soon after their discovery in lymphoid tissues by Steinman and Cohn, as cells with the unique ability to prime naïve antigen-specific T cells, it was realized that DC can exist in at least two...

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Autores principales: Dalod, Marc, Chelbi, Rabie, Malissen, Bernard, Lawrence, Toby
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193918/
https://ncbi.nlm.nih.gov/pubmed/24737868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201488027
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